Abilify and Compulsive Gambling

Abilify and Compulsive Gambling

Abilify (aripiprazole) is an atypical antipsychotic drug. The FDA approved Abilify in 2002 to treat bipolar schizophrenia and later approved it for Bipolar disorder, irritability associated with autistic disorder, and Major Depressive Disorder.

Abilify is a partial and full dopamine agonist. Aripiprazole works by partially blocking dopamine at the D2 receptor and stimulating the D3 dopamine receptor. The result of over stimulating the D3 receptor is that it can cause compulsive behaviors including compulsive gambling, eating, shopping and hypersexuality.

In 2012, the European Medicines Agency required a new warning label to be added to the label to address the compulsive behaviors some patients were experiencing. Health Canada took similar measures in 2015 and added a warning of pathological gambling to its label.

Despite dozens of other countries adding a warning for compulsive behavior, a warning was not added to the U.S. label until 2016.

Meshbesher & Spence is investigating cases in which the primary loss is gambling and the losses occurred prior to May of 2016. Losses from gambling can include bankruptcies, home foreclosures, unnecessary mortgages, wage loss, emptied bank accounts or 401(k) accounts and criminal charges.

 

Should I stop taking Abilify?

Never stop taking a prescription medication without talking to your health care provider. Changing your medication could result in severe adverse consequences. You and your doctor should make the decision whether Abilify is for you.

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